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1

Reduced sensitivity of Niemann-Pick

Yuki Ohsaki, Yuko Sugimoto, Michitaka Suzuki, Toshiyuki Kaidoh, Yukiko Shimada, Yoshiko Ohno-Iwashita, JoannaP. Davies, YiannisA. Ioannou, Kousaku Ohno, Haruaki Ninomiya

Journal:

Histochemistry and Cell Biology

Year:

2004

Language:

english

File:

PDF, 1.40 MB

english, 2004

2

Cellular aging-dependent decrease in cholesterol in membrane microdomains of human diploid fibroblasts

Megumi Nakamura, Hiroshi Kondo, Yukiko Shimada, Abdul A Waheed, Yoshiko Ohno-Iwashita

Journal:

Experimental Cell Research

Year:

2003

Language:

english

File:

PDF, 666 KB

english, 2003

3

Cross-Linking of Plasmalemmal Cholesterol in Lymphocytes Induces Capping, Membrane Shedding, and Endocytosis through Coated Pits

Haruo Hagiwara, Shin-ya Kogure, Megumi Nakamura, Yukiko Shimada, Yoshiko Ohno-Iwashita, Toyoshi Fujimoto

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 473 KB

english, 1999

4

Detection of cholesterol-rich microdomains in the inner leaflet of the plasma membrane

Masami Hayashi, Yukiko Shimada, Mitsushi Inomata, Yoshiko Ohno-Iwashita

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 491 KB

english, 2006

5

Interaction of .theta.-Toxin (Perfringolysin O), a Cholesterol-Binding Cytolysin, with Liposomal Membranes: Change in the Aromatic Side Chains upon Binding and Insertion

Nakamura, Megumi, Sekino, Naoko, Iwamoto, Machiko, Ohno-Iwashita, Yoshiko

Journal:

Year:

1995

Language:

english

File:

PDF, 1.36 MB

english, 1995

6

Contribution of Histidine Residues to Oligomerization of θ-Toxin (Perfringolysin O), a Cholesterol-Binding Cytolysin

NAKAMURA, Megumi, SEKINO-SUZUKI, Naoko, SHIMADA, Yukiko, OHNO-IWASHITA, Yoshiko

Journal:

Bioscience Biotechnology and Biochemistry

Year:

1999

File:

PDF, 970 KB

1999

7

Partial blockage of sterol biosynthesis with a squalene synthase inhibitor in early postnatal Niemann-Pick type C npcnih null mice brains reduces neuronal cholesterol accumulation, abrogates astrogliosis, but may inhibit myelin maturation

Patrick C. Reid, Song Lin, Marie T. Vanier, Yoshiko Ohno-Iwashita, H. James Harwood Jr., William F. Hickey, Catherine C.Y. Chang, Ta Yuan Chang

Journal:

Journal of Neuroscience Methods

Year:

2008

Language:

english

File:

PDF, 3.62 MB

english, 2008

8

Sequestration of Cross-linked Membrane Molecules to Caveolae in Two Different Pathways

Aoki, Takeo, Kogure, Shin-ya, Kogo, Hiroshi, Hayashi, Masami, Ohno-Iwashita, Yoshiko, Fujimoto, Toyoshi

Journal:

Acta Histochemica et Cytochemica

Year:

2003

Language:

english

File:

PDF, 2.36 MB

english, 2003

9

Author Correction: A spatial similarity of stereochemical environments formed by amino acid residues defines a common epitope of two non-homologous proteins

Nakashima, Kentaro, Iwashita, Shintaro, Suzuki, Takehiro, Kato, Chieko, Kohno, Toshiyuki, Kamei, Yasutomi, Sasaki, Motoki, Urayama, Osamu, Ohno-Iwashita, Yoshiko, Dohmae, Naoshi, Song, Si-Young

Journal:

Scientific Reports

Year:

2020

File:

PDF, 757 KB

2020

10

Effect of isolated C-terminal fragment of θ-toxin (perfringolysin O) on toxin assembly and membrane lysis

Machiko IWAMOTO, Yoshiko OHNO-IWASHITA, Susumu ANDO

Journal:

Year:

1990

Language:

english

File:

PDF, 837 KB

english, 1990

11

A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system

Werner, Hauke B., Krämer-Albers, Eva-Maria, Strenzke, Nicola, Saher, Gesine, Tenzer, Stefan, Ohno-Iwashita, Yoshiko, De Monasterio-Schrader, Patricia, Möbius, Wiebke, Moser, Tobias, Griffiths, Ian R.,

Journal:

Year:

2013

Language:

english

File:

PDF, 22.54 MB

english, 2013

12

The C-terminal domain of perfringolysin O is an essential cholesterol-binding unit targeting to cholesterol-rich microdomains

Yukiko Shimada, Mikako Maruya, Shintaro Iwashita, Yoshiko Ohno-Iwashita

Journal:

Year:

2002

Language:

english

File:

PDF, 242 KB

english, 2002

13

Membrane disorganization induced by perfringolysin O (theta-toxin) of Clostridium perfringens — effect of toxin binding and self-assembly on liposomes

Machiko Iwamoto, Megumi Nakamura, Ken-ichiro Mitsui, Susumu Ando, Yoshiko Ohno-Iwashita

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1993

Language:

english

File:

PDF, 754 KB

english, 1993

14

Lipid binding activity of a neuron-specific protein NAP-22 studied in vivo and in vitro

Akira Terashita, Nobuo Funatsu, Masato Umeda, Yukiko Shimada, Yoshiko Ohno-Iwashita, Richard M. Epand, Shohei Maekawa

Journal:

Journal of Neuroscience Research

Year:

2002

Language:

english

File:

PDF, 1.77 MB

english, 2002

15

Detachment-associated changes in lipid rafts of senescent human fibroblasts

Mitsushi Inomata, Yukiko Shimada, Masami Hayashi, Hiroshi Kondo, Yoshiko Ohno-Iwashita

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 207 KB

english, 2006

16

Cold-labile hemolysin produced by limited proteolysis of .theta.-toxin from Clostridium perfringens

Ohno-Iwashita, Yoshiko, Iwamoto, Machiko, Mitsui, Kenichiro, Kawasaki, Hiroshi, Ando, Susumu

Journal:

Year:

1986

Language:

english

File:

PDF, 1.34 MB

english, 1986

17

Erratum to “A biotinylated perfringolysin O derivative: a new probe for detection of cell surface cholesterol”: [Biochim. Biophys. Acta 1327 (1997) 222–230]

Machiko Iwamoto, Ikuo Morita, Mitsugu Fukuda, Sei-itsu Murota, Susumu Ando, Yoshiko Ohno-Iwashita

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1998

Language:

english

File:

PDF, 418 KB

english, 1998

18

Localization of Cholesterol-rich Membranes by Immunoelectron Microscopy

Möbius, Wiebke, van Donselaar, Elly, Ohno-Iwashita, Yoshiko, Shimada, Yukiko, Heijnen, Harry, Slot, Jan W., Geuze, Hans J.

Journal:

Microscopy and Microanalysis

Year:

2003

Language:

english

File:

PDF, 45 KB

english, 2003

19

Ultrastructural localization of flotillin-1 to cholesterol-rich membrane microdomains, rafts, in rat brain tissue

Hideko Kokubo, J.Bernd Helms, Yoshiko Ohno-Iwashita, Yukiko Shimada, Yuko Horikoshi, Haruyasu Yamaguchi

Journal:

Year:

2003

Language:

english

File:

PDF, 997 KB

english, 2003

20

Contribution of Individual Tryptophan Residues to the Structure and Activity of θ-Toxin (Perfringolysin O), A Cholesterol-Binding Cytolysin

Naoko Sekino-Suzuki, Megumi Nakamura, Ken-ichiro Mitsui, Yoshiko Ohno-Iwashita

Journal:

Year:

1996

Language:

english

File:

PDF, 1.20 MB

english, 1996

21

Comparative studies on the structures of colicins E2 and E3

Yoshiko Ohno-Iwashita, Kazutomo Imahori

Journal:

Year:

1979

Language:

english

File:

PDF, 287 KB

english, 1979

22

Fluorescent probes for superresolution imaging of lipid domains on the plasma membrane

Mizuno, Hideaki, Abe, Mitsuhiro, Dedecker, Peter, Makino, Asami, Rocha, Susana, Ohno-Iwashita, Yoshiko, Hofkens, Johan, Kobayashi, Toshihide, Miyawaki, Atsushi

Journal:

Chemical Science

Year:

2011

Language:

english

File:

PDF, 372 KB

english, 2011

23

Processing of preproteins by liposomes bearing leader peptidase

Ohno-Iwashita, Yoshiko, Wolfe, Paul, Ito, Koreaki, Wickner, William

Journal:

Year:

1984

Language:

english

File:

PDF, 3.44 MB

english, 1984

24

Plasma membrane microdomains in aging and disease

Yoshiko Ohno-Iwashita, Yukiko Shimada, Masami Hayashi, Mitsushi Inomata

Journal:

Geriatrics & Gerontology International

Year:

2010

Language:

english

File:

PDF, 461 KB

english, 2010

25

Age-associated up-regulation of a negative co-stimulatory receptor PD-1 in mouse CD4+ T cells

Yukiko Shimada, Masami Hayashi, Yasuhiko Nagasaka, Yoshiko Ohno-Iwashita, Mitsushi Inomata

Journal:

Experimental Gerontology

Year:

2009

Language:

english

File:

PDF, 816 KB

english, 2009

26

Protease-nicked O-toxin of Clostridium perfringens, a new memnrane probe with no cytoltic effect, revcals two classes of cholesterol as toxin-binding sites on sheep erythrocytes

Yoshiko OHNO-IWASHITA, Machiko IWAMOTO, Ken-ichiro MITSUI, Susumu ANDO, Yoshitaka NAGAI

Journal:

Year:

1988

Language:

english

File:

PDF, 1.19 MB

english, 1988

27

A modified θ-toxin produced by limited proteolysis and methylation: a probe for the functional study of membrane cholesterol

Yoshiko Ohno-Iwashita, Machiko Iwamoto, Susumu Ando, Ken-ichiro Mitsui, Shintaro Iwashita

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1990

Language:

english

File:

PDF, 886 KB

english, 1990

28

Crystallization and preliminary X-ray diffraction studies of θ-toxin (perfringolysin O), a pore-forming cytolysin of Clostridium perfringens

Mitsuaki Sugahara, Naoko Sekino-Suzuki, Yoshiko Ohno-Iwashita, Kunio Miki

Journal:

Journal of Crystal Growth

Year:

1996

Language:

english

File:

PDF, 498 KB

english, 1996

29

Axon-dominant localization of cell-surface cholesterol in cultured hippocampal neurons and its disappearance in Niemann–Pick type C model cells

Yuichi Tashiro, Tsuneo Yamazaki, Yukiko Shimada, Yoshiko Ohno-Iwashita, Koichi Okamoto

Journal:

European Journal of Neuroscience

Year:

2004

Language:

english

File:

PDF, 800 KB

english, 2004

30

In vitro protein synthesis at elevated temperature by an extract of an extreme thermophile: Effects of polyamines on the polyuridylic acid-directed reaction

Yoshiko Ohno-Iwashita, Tairo Oshima, Kazutomo Imahori

Journal:

Archives of Biochemistry and Biophysics

Year:

1975

Language:

english

File:

PDF, 837 KB

english, 1975

31

Visualization of Sterol-Rich Membrane Domains with Fluorescently-Labeled Theonellamides

Nishimura, Shinichi, Ishii, Kumiko, Iwamoto, Kunihiko, Arita, Yuko, Matsunaga, Shigeki, Ohno-Iwashita, Yoshiko, Sato, Satoshi B., Kakeya, Hideaki, Kobayashi, Toshihide, Yoshida, Minoru, Liu, Jun

Journal:

Year:

2013

Language:

english

File:

PDF, 820 KB

english, 2013

32

2P240 Single-molecule tracking and detection of transient colocalization of cholesterol in the live-cell plasma membrane(Cell biological problems-adhesion, motility, cytoskeleton, signaling, and membrane,Oral Presentations)

Nemoto, Yuri L., Koyama-Honda, Ikuko, Sanematsu, Fumiyuki, Shimada, Yukiko, Yahara, Masako, Ohno-Iwashita, Yoshiko, Kusumi, Akihiro

Journal:

Seibutsu Butsuri

Year:

2007

Language:

english

File:

PDF, 236 KB

english, 2007

33

Effect of lipidic factors on membrane cholesterol topology — mode of binding of θ-toxin to cholesterol in liposomes

Yoshiko Ohno-Iwashita, Machiko Iwamoto, Susumu Ando, Shintaro Iwashita

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1992

Language:

english

File:

PDF, 1.43 MB

english, 1992

34

Assignment of the functional loci in colicin E2 and E3 molecules by the characterization of their proteolytic fragments

Ohno-Iwashita, Yoshiko, Imahori, Kazutomo

Journal:

Year:

1980

Language:

english

File:

PDF, 2.60 MB

english, 1980

35

A Cytolysin, Θ-Toxin, Preferentially Binds to Membrane Cholesterol Surrounded by Phospholipids with 18-Carbon Hydrocarbon Chains in Cholesterol-Rich Region1

Ohno-Iwashita, Yoshiko, Iwamoto, Machiko, Mitsui, Ken-ichiro, Ando, Susumu, Iwashita, Shintaro

Journal:

Journal of Biochemistry

Year:

1991

Language:

english

File:

PDF, 2.11 MB

english, 1991

36

Perfringolysin O, a cholesterol-binding cytolysin, as a probe for lipid rafts

Yoshiko Ohno-Iwashita, Yukiko Shimada, A.Abdul Waheed, Masami Hayashi, Mitsushi Inomata, Megumi Nakamura, Mikako Maruya, Shintaro Iwashita

Journal:

Year:

2004

Language:

english

File:

PDF, 397 KB

english, 2004

37

Role of the essential thiol group in the thiol-activated cytolysin from Clostridium perfringens

Machiko IWAMOTO, Yoshiko OHNO-IWASHITA, Susumu ANDO

Journal:

Year:

1987

Language:

english

File:

PDF, 725 KB

english, 1987

38

γ-Secretase Activity Is Present in Rafts but Is Not Cholesterol-Dependent †

Wada, Satoko, Morishima-Kawashima, Maho, Qi, Yue, Misono, Hiroaki, Shimada, Yukiko, Ohno-Iwashita, Yoshiko, Ihara, Yasuo

Journal:

Year:

2003

Language:

english

File:

PDF, 217 KB

english, 2003

39

Distinct localization of lipid rafts and externalized phosphatidylserine at the surface of apoptotic cells

Hidenari Ishii, Tomoe Mori, Akiko Shiratsuchi, Yuji Nakai, Yukiko Shimada, Yoshiko Ohno-Iwashita, Yoshinobu Nakanishi

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 398 KB

english, 2005

40

A biotinylated perfringolysin O derivative: A new probe for detection of cell surface cholesterol

Machiko Iwamoto, Ikuo Morita, Mitsugu Fukuda, Sei-itsu Murota, Susumu Ando, Yoshiko Ohno-Iwashita

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1997

Language:

english

File:

PDF, 432 KB

english, 1997

41

Accelerated Aβ aggregation in the presence of GM1-ganglioside-accumulated synaptosomes of aged apoE4-knock-in mouse brain

Naoki Yamamoto, Urule Igbabvoa, Yukiko Shimada, Yoshiko Ohno-Iwashita, Mariko Kobayashi, W.Gibson Wood, Shinobu C Fujita, Katsuhiko Yanagisawa

Journal:

Year:

2004

Language:

english

File:

PDF, 271 KB

english, 2004

42

Impairment in a negative regulatory system for TCR signaling in CD4+ T cells from old mice

Mitsushi Inomata, Yukiko Shimada, Masami Hayashi, Jun Shimizu, Yoshiko Ohno-Iwashita

Journal:

Year:

2007

Language:

english

File:

PDF, 341 KB

english, 2007

43

A spatial similarity of stereochemical environments formed by amino acid residues defines a common epitope of two non-homologous proteins

Nakashima, Kentaro, Iwashita, Shintaro, Suzuki, Takehiro, Kato, Chieko, Kohno, Toshiyuki, Kamei, Yasutomi, Sasaki, Motoki, Urayama, Osamu, Ohno-Iwashita, Yoshiko, Dohmae, Naoshi, Song, Si-Young

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 2.02 MB

english, 2019

44

Separation of a cholesterol-enriched microdomain involved in T-cell signal transduction

Yukiko Shimada, Mitsushi Inomata, Hidenori Suzuki, Masami Hayashi, A. Abdul Waheed, Yoshiko Ohno-Iwashita

Journal:

Year:

2005

Language:

english

File:

PDF, 308 KB

english, 2005

45

Involvement of Calpain in Integrin-Mediated Signal Transduction

Mitsushi Inomata, Masami Hayashi, Yoshiko Ohno-Iwashita, Satoshi Tsubuki, Takaomi C. Saido, Seiichi Kawashima

Journal:

Archives of Biochemistry and Biophysics

Year:

1996

Language:

english

File:

PDF, 178 KB

english, 1996

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